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Article

Adiponectin receptor 1 gene (ADIPOR1) as a candidate for type 2 diabetes and insulin resistance.

Diabetes - 1 Aug 2004

Wang Hua, Zhang Hailing, Jia Yiwen, Zhang Zhengxian, Craig Rebekah, Wang Xiaoqin, Elbein Steven C

Abstract excerpt

Considerable data support adiponectin as an important adipose-derived insulin sensitizer that enhances fatty acid oxidation and alters hepatic gluconeogenesis. Adiponectin acts by way of two receptors, ADIPOR1 and ADIPOR2. ADIPOR1 is widely expressed in tissues, including muscle, liver, and pancreas, and binds the globular form of adiponectin with high affinity. To test the hypothesis that sequence variations in...

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Source

Identifiers

PMID: 15277397
DOI: 10.2337/diabetes.53.8.2132

Genes

ADIPOR1
ADIPOR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Adiponectin receptor 1 gene (ADIPOR1) as a candidate for type 2 diabetes and insulin resistance.PMID 15277397Read ↗

Genetic analysis of ADIPOR1 and ADIPOR2 candidate polymorphisms for type 2 diabetes in the Caucasian population.Semantic proximity Read ↗

Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.Semantic proximity Read ↗

Polymorphisms of ADIPOR1 and ADIPOR2 are associated with phenotypes of type 2 diabetes in Koreans.Semantic proximity Read ↗

Adiponectin receptor 1 variants associated with lower insulin resistance in African Americans.Semantic proximity Read ↗

Single-nucleotide polymorphisms in adiponectin, AdipoR1, and AdipoR2 genes: insulin resistance and type 2 diabetes mellitus candidate genes.Semantic proximity Read ↗

Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance.Semantic proximity Read ↗

Genetic variants of adiponectin receptor 2 are associated with increased adiponectin levels and decreased triglyceride/VLDL levels in patients with metabolic syndrome.Semantic proximity Read ↗

Adiponectin and adiponectin receptors in obesity-linked insulin resistance.Semantic proximity Read ↗

Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes.Semantic proximity Read ↗

A comprehensive investigation of variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/R2), and their association with serum adiponectin, type 2 diabetes, insulin resistance and the metabolic syndrome.Semantic proximity Read ↗

Common variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/2), adiponectin concentrations, and diabetes incidence in the Diabetes Prevention Program.Semantic proximity Read ↗

Association of polymorphisms at the ADIPOR1 regulatory region with type 2 diabetes and body mass index in a Brazilian population with European or African ancestry.Semantic proximity Read ↗

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