Article
Adiponectin receptor 1 variants associated with lower insulin resistance in African Americans.
Obesity (Silver Spring, Md.) - 1 Aug 2007
Crimmins Nancy A, Woo Jessica G, Kaushal Ritesh D, Deka Ranjan, Dolan Lawrence M, Martin Lisa J
Abstract excerpt
Adiponectin has been shown to have a role in insulin resistance. However, little is known about the contribution of genetic variation in the adiponectin receptor 1 gene (ADIPOR1) in this regard. We hypothesized that variation in ADIPOR1 would be associated with significant changes in insulin resistance and tested this hypothesis in a cohort of 483 African-American adolescents. Seven single nucleotide...
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