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Article

Adiponectin, type 2 diabetes and the metabolic syndrome: lessons from human genetic studies.

Expert reviews in molecular medicine - 20 Nov 2006

Vasseur Francis, Meyre David, Froguel Philippe

Abstract excerpt

Adiponectin, a protein exclusively secreted by adipose tissue but present at low levels in obesity, is now widely recognised as a key determinant of insulin sensitivity and of protection against obesity-associated metabolic syndrome. In this review we explain how genetic findings have contributed to a better understanding of the physiological role of adiponectin in humans. The adiponectin-encoding gene, ADIPOQ...

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Topics

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

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Share to Genetic Predisposition to Disease

Share to Genetics, Medical

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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 17112391
DOI: 10.1017/S1462399406000147

Genes

ADIPOQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Adiponectin, type 2 diabetes and the metabolic syndrome: lessons from human genetic studies.PMID 17112391Read ↗

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Association of ADIPOQ gene variants with body weight, type 2 diabetes and serum adiponectin concentrations: the Finnish Diabetes Prevention Study.Semantic proximity Read ↗

Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease.Semantic proximity Read ↗

A comprehensive investigation of variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/R2), and their association with serum adiponectin, type 2 diabetes, insulin resistance and the metabolic syndrome.Semantic proximity Read ↗

Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation.Semantic proximity Read ↗

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