Article
Single-nucleotide polymorphisms and haplotypes in the adiponectin gene contribute to the genetic risk for type 2 diabetes in Tunisian Arabs.
Diabetes research and clinical practice - 1 Aug 2012
Mtiraoui Nabil, Ezzidi Intissar, Turki Amira, Chaieb Arbi, Mahjoub Touhami, Almawi Wassim Y
Abstract excerpt
Adiponectin is an adipocyte-produced protein involved in regulating glucose, lipid, and energy metabolism, and is encoded by ADIPOQ (APM1) gene. ADIPOQ polymorphisms were previously associated with type 2 diabetes (T2DM) in Caucasian and non-Caucasian populations. We investigated the contribution of 13 polymorphisms in the promoter, coding regions, and 3'untranslated region of ADIPOQ gene to T2DM in 917 patients...
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