Article
The 3'-UTR of the adiponectin Q gene harbours susceptibility loci for atherosclerosis and its metabolic risk traits.
BMC medical genetics - 13 Dec 2013
Muiya Nzioka, Al-Najai Mohammed, Tahir Asma I, Elhawari Samar, Gueco Daisy, Andres Editha, Mazhar Nejat, Altassan Nada, Meyer Brian F, Alshahid Maie, Dzimiri Nduna
Abstract excerpt
BACKGROUND: Adiponectin Q is a hormone that modulates several metabolic processes and contributes to the suppression of biochemical pathways leading to metabolic syndrome. Hence, polymorphic changes in the adiponectin Q (ADIPOQ) gene are likely to contribute to metabolic disorders, and consequently lead to atherosclerosis. In the present study, we performed a population-based association study for 8 SNPs in 4646...
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