Article
The relationship between glucocorticoid receptor polymorphisms, stressful life events, social support, and post-traumatic stress disorder.
BMC psychiatry - 12 Aug 2014
Lian Yulong, Xiao Jing, Wang Qian, Ning Li, Guan Suzhen, Ge Hua, Li Fuye, Liu Jiwen
Abstract excerpt
BACKGROUND: It is debatable whether or not glucocorticoid receptor (GR) polymorphisms moderate susceptibility to PTSD. Our objective was to examine the effects of stressful life events, social support, GR genotypes, and gene-environment interactions on the etiology of PTSD. METHODS: Three tag single nucleotide polymorphisms, trauma events, stressful life events, and social support were assessed in 460 patients...
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