Article
Serotonin transporter gene (SLC6A4) promoter polymorphisms and the susceptibility to posttraumatic stress disorder in the general population.
The American journal of psychiatry - 1 Aug 2009
Grabe Hans Jörgen, Spitzer Carsten, Schwahn Christian, Marcinek Agnes, Frahnow Antje, Barnow Sven, Lucht Michael, Freyberger Harald Jürgen, John Ulrich, Wallaschofski Henri, Völzke Henry, Rosskopf Dieter
Abstract excerpt
OBJECTIVE: There has been debate whether polymorphisms within the serotonin transporter-linked polymorphic region (5-HTTLPR) moderate susceptibility to posttraumatic stress disorder (PTSD). The authors investigated 5-HTTLPR genotypes and their interaction with the number of traumatic events in the prediction of PTSD in a general population sample. METHOD: Analyses were based on data from 3,045 subjects who...
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