Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identifying differential interactions of potentially traumatic experiences with genetic risk for posttraumatic stress disorder.

European journal of psychotraumatology - 1 Dec 2026

Knyspel Jacob, Kakar Saakshi, Carnegie Anna, Kalsi Gursharan, Meldrum Laura, Smith Iona, Bristow Shannon, Davies Molly R, Armour Chérie, BioResource Nihr, Eley Thalia C, Breen Gerome, Wong Chloe C Y, Coleman Jonathan R I

Abstract excerpt

Background: Posttraumatic stress disorder (PTSD) occurs following potentially traumatic experiences, but not everyone who experiences trauma develops PTSD. Genetic factors play an important role in shaping how individuals respond to trauma, reflecting gene-environment interaction. An open and important question in PTSD genetics research is the extent to which gene-environment interactions vary across specific...

Read the complete abstract on PubMed

Topics

Humans
Stress Disorders, Post-Traumatic
Gene-Environment Interaction
Female
United Kingdom

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Middle Aged

Genetic Predisposition to Disease

Genetic Risk Score

Adult

Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 42748958
DOI: 10.1080/20008066.2026.2709319
PMCID: PMC13587574

Genes

DTX4
FAM120A
PSMD12
SGCD
TYW3
ZNF660

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identifying differential interactions of potentially traumatic experiences with genetic risk for posttraumatic stress disorder.PMID 42748958Read ↗

Implications of gene × environment interactions in post-traumatic stress disorder risk and treatment.Semantic proximity Read ↗

Trauma Matters: Integrating Genetic and Environmental Components of PTSDSemantic proximity Read ↗

Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information.Semantic proximity Read ↗

Biological underpinnings of trauma and post-traumatic stress disorder: focusing on genetics and epigenetics.Semantic proximity Read ↗

Gene-environment interaction in posttraumatic stress disorder: review, strategy and new directions for future research.Semantic proximity Read ↗

Disentangling the roles of trauma and genetics in psychiatric disorders using an Electronic Health Records-based approachSemantic proximity Read ↗

Recent Genetics and Epigenetics Approaches to PTSD.Semantic proximity Read ↗

Genetic and environmental influences on trauma exposure and posttraumatic stress disorder symptoms: a twin study.Semantic proximity Read ↗

Common heritable contributions to low-risk trauma, high-risk trauma, posttraumatic stress disorder, and major depression.Semantic proximity Read ↗

Gene-Environment Correlation Across Trauma Subtypes and Developmental Timing: Evidence From the EU-GEI and ALSPAC.Semantic proximity Read ↗

The interaction between polygenic risk score and trauma affects the likelihood of post-traumatic stress disorder in female victims of sexual assault.Semantic proximity Read ↗

Genomic Approaches to Posttraumatic Stress Disorder: The Psychiatric Genomic Consortium Initiative.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.