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Article

Inhibition of hepatitis C virus replication by single-stranded RNA structural mimics.

World journal of gastroenterology - 7 May 2010

Smolic Robert, Smolic Martina, Andorfer John H, Wu Catherine H, Smith Robert M, Wu George Y

Abstract excerpt

AIM: To examine the effect of hepatitis C virus (HCV) structural mimics of regulatory regions of the genome on HCV replication. METHODS: HCV RNA structural mimics were constructed and tested in a HCV genotype 1b aBB7 replicon, and a Japanese fulminant hepatitis-1 (JFH-1) HCV genotype 2a infection model. All sequences were computer-predicted to adopt stem-loop structures identical to the corresponding elements in...

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Identifiers

PMID: 20440850
DOI: 10.3748/wjg.v16.i17.2100
PMCID: PMC2864835

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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