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Article

Genetic architecture of quantitative traits in mice, flies, and humans.

Genome research - 1 May 2009

Flint Jonathan, Mackay Trudy F C

Abstract excerpt

We compare and contrast the genetic architecture of quantitative phenotypes in two genetically well-characterized model organisms, the laboratory mouse, Mus musculus, and the fruit fly, Drosophila melanogaster, with that found in our own species from recent successes in genome-wide association studies. We show that the current model of large numbers of loci, each of small effect, is true for all species examined,...

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Identifiers

PMID: 19411597
DOI: 10.1101/gr.086660.108
PMCID: PMC3647534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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