Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The significance of the homozygous CYP2A6 deletion on nicotine metabolism: a new genotyping method of CYP2A6 using a single PCR-RFLP.

Biochemical and biophysical research communications - 19 Aug 1999

Kitagawa K, Kunugita N, Katoh T, Yang M, Kawamoto T

Abstract excerpt

A convenient and specific CYP2A6 genotyping method was developed in this study. This method consisting of a single PCR-RFLP is capable of resolving the genotype into either CYP2A6*1 (wild type), CYP2A6*2, or CYP2A6*3. Among 252 Japanese persons genotyped, 241 were genotyped as the wild type, 1 as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Cotinine
Share to Cytochrome P-450 CYP2A6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 Enzyme System

Share to Mixed Function Oxygenases

Share to Nicotine

Share to Sequence Deletion

Share to Smoking

Source

Identifiers

PMID: 10448083
DOI: 10.1006/bbrc.1999.1182

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10448083-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The significance of the homozygous CYP2A6 deletion on nicotine metabolism: a new genotyping method of CYP2A6 using a single PCR-RFLP.PMID 10448083Read ↗

Effects of whole deletion of CYP2A6 on nicotine metabolism in humans.Semantic proximity Read ↗

Novel human CYP2A6 alleles confound gene deletion analysis.Semantic proximity Read ↗

CYP2A7 polymorphic alleles confound the genotyping of CYP2A6*4A allele.Semantic proximity Read ↗

Association between nicotine metabolism and CYP2A6*1 and CYP2A6*4 genotypes in an Iranian population.Semantic proximity Read ↗

Genotyping of wild-type cytochrome P450 2A6 and whole-gene deletion using human blood samples and a multiplex real-time polymerase chain reaction method with dual-labeled probes.Semantic proximity Read ↗

Functional variants at CYP2A6: new genotyping methods, population genetics, and relevance to studies of tobacco dependence.Semantic proximity Read ↗

CYP2A6 genetic variation and potential consequences.Semantic proximity Read ↗

Duplications and defects in the CYP2A6 gene: identification, genotyping, and in vivo effects on smoking.Semantic proximity Read ↗

Association of CYP2A6 gene deletion with cigarette smoking status in Japanese adults.Semantic proximity Read ↗

The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans.Semantic proximity Read ↗

Genetic variability in CYP2A6 and the pharmacokinetics of nicotine.Semantic proximity Read ↗

Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.