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Article

Association of T-cell regulatory gene polymorphisms with oral squamous cell carcinoma.

Oral oncology - 1 Jul 2010

Kämmerer Peer W, Toyoshima Takeshi, Schöder Fabian, Kämmerer Philipp, Kuhr Kathrin, Brieger Jürgen, Al-Nawas Bilal

Abstract excerpt

Costimulatory molecules have complementary effects on T-cell activation and their balance may control the development of oral cancer. The aim of this study was to determine the relevance of cytotoxic T-lymphocyte antigen 4 (CTLA-4), CD28 and inducible costimulator (ICOS) polymorphisms in oral squamous cell carcinoma (OSCC). Genotyping for CTLA-4 (-1661 A/G and +49 A/G), CD28 (0 C/G and +3160 G/T) and ICOS (+637...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

Share to CTLA-4 Antigen

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Share to Mouth Neoplasms

Share to T-Lymphocytes, Cytotoxic

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Source

Identifiers

PMID: 20435510
DOI: 10.1016/j.oraloncology.2010.03.025

Genes

ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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