Article
Polymorphism of costimulatory molecules (CTLA4, ICOS, PD.1 and CD28) and allogeneic hematopoietic stem cell transplantation in Iranian patients.
Immunological investigations - 1 Jan 2014
Iravani-Saadi Mahdiyar, Karimi Mohammad Hossein, Yaghobi Ramin, Geramizadeh Bita, Ramzi Mani, Niknam Ahmad, Pourfathollah Arefeh
Abstract excerpt
Costimulatory molecules are important factors determining the outcome of bone marrow transplant. Because the host ability in costimulatory molecule function may be affected by gene polymorphisms, the aim of the present study was to investigate the effect of CTLA4, ICOS, PD.1 and CD28 gene polymorphisms in outcome of bone marrow transplant patients. A total of 72 recipients were included in this study. CTLA4...
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