Article
Potential role of immune cell genetic variants associated with tumor microenvironment response in laryngeal squamous cell carcinoma (LSCC) in terms of clinicopathological features.
Pathology, research and practice - 1 Dec 2021
Horozoglu Cem, Sonmez Dilara, Demirkol Seyda, Hakan Mehmet Tolgahan, Kaleler Islim, Hepokur Ceylan, Verim Aysegul, Yaylim Ilhan
Abstract excerpt
Immunomodulatory signals regulate the self-tolerance, activation, priming and survival processes of T cells. Programmed cell death protein 1 (PD1), Programmed death-ligand 1 (PD-L1) inhibitory signals and CD27, CD28 costimulators have been detected for many solid organ cancers in tumor-infiltrating T cells. It was aimed to investigate the immune cell-based regulatory genetic variants in laryngeal squamous cell...
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