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Article

Characterization of CD28, CTLA4, and ICOS polymorphisms in three Brazilian ethnic groups.

Human immunology - 1 Jul 2005

Guzman V B, Morgun A, Shulzhenko N, Mine K L, Gonçalves-Primo A, Musatti C C, Gerbase-Delima M

Abstract excerpt

Costimulatory molecules CD28, CTLA-4 (cytotoxic T-lymphocyte-associated antigen-4), and ICOS (inducible costimulator) genes lie within the 300-kb chromosome region 2q33. CD28, CTLA-4, and ICOS have been described to be important regulators of T-cell activation. With the objective to study ethnic variations in allelic frequencies and linkage disequilibrium (LD) patterns, we genotyped CD28 intron 3 (+17 T>C), CTLA4...

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Source

Identifiers

PMID: 16112024
DOI: 10.1016/j.humimm.2005.04.007

Genes

CTLA4
ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Characterization of CD28, CTLA4, and ICOS polymorphisms in three Brazilian ethnic groups.PMID 16112024Read ↗

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