Article
Gene expression polymorphisms of interleukins-1 beta, -4, -6, -8, -10, and tumor necrosis factors-alpha, -beta: regression analysis of their effect upon oral squamous cell carcinoma.
Journal of cancer research and clinical oncology - 1 Aug 2008
Vairaktaris Eleftherios, Yapijakis Christos, Serefoglou Zoe, Avgoustidis Dimitrios, Critselis Elena, Spyridonidou Sofia, Vylliotis Antonis, Derka Spyridoula, Vassiliou Stavros, Nkenke Emeka, Patsouris Efstratios
Abstract excerpt
PURPOSE: Functional DNA polymorphisms affecting gene expression and serum or saliva levels of interleukins IL-1 beta,-4,-6,-8,-10 and tumor necrosis factors TNF-alpha,-beta have been associated with increased risk for the development of oral squamous cell carcinoma (OSCC). The present retrospective case-control study examines possible interactions between seven cytokine genotype polymorphisms and their...
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