Article
Functional genetic variants of CTLA-4 and risk of tobacco-related oral carcinoma in high-risk North Indian population.
Human immunology - 1 Mar 2013
Bharti Vijaya, Mohanti Bidhu Kalyan, Das Satya Narayan
Abstract excerpt
Single nucleotide polymorphisms (SNPs) of the CTLA-4 gene have been implicated in susceptibility to different cancer in different ethnic populations. We assessed the association of five SNPs [-1722C/T, -1661A/G and -318C/T in the promoter region49A/G in exon 1 and CT60A/G in the 3'untranslated region (UTR)] with tobacco-related oral squamous cell carcinoma (OSCC) in North Indian subjects. We genotyped 130 OSCC...
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