Article
The BDNF Val66Met polymorphism is an independent risk factor for high lethality in suicide attempts of depressed patients.
Progress in neuro-psychopharmacology & biological psychiatry - 16 Aug 2010
Schenkel Laila Cigana, Segal Jair, Becker Juliana Allebrand, Manfro Gisele Gus, Bianchin Marino Muxfeldt, Leistner-Segal Sandra
Abstract excerpt
Some authors have reported an association of BDNF Val66Met polymorphism with suicidal behavior and/or clinical aspects of suicidal attempts. We evaluated, here, the impact of BDNF Val66Met polymorphism on the clinical characteristics of suicide attempts. The study was conducted on a cohort of 120 consecutive patients who were admitted to the Emergency Hospital of Porto Alegre, Brazil, due to a suicide attempt....
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