Article
Interaction between BDNF Val66Met and childhood trauma on adult's violent suicide attempt.
Genes, brain, and behavior - 1 Apr 2008
Perroud N, Courtet P, Vincze I, Jaussent I, Jollant F, Bellivier F, Leboyer M, Baud P, Buresi C, Malafosse A
Abstract excerpt
Genetic factors, specially those related to serotoninergic activities, and childhood maltreatment have both been implicated in suicidal behaviour (SB). However, little attention has been paid to the possible interaction between genes and childhood maltreatment in the comprehension of SB. Brain-derived neurotrophic factor (BDNF) plays an important role in the growth of serotoninergic neurons during childhood and...
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