Article
Association between serotonin-related gene polymorphisms and suicidal behavior in depressive patients.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Jul 2008
Yoon Ho-Kyoung, Kim Yong-Ku
Abstract excerpt
BACKGROUND: Several studies have suggested that there is a substantial genetic contribution to suicidal behavior. Genes encoding proteins involved in serotonergic transmission are major candidates in association studies of suicidal behavior. In this study, we aimed to investigate the 5-HT2A receptor (5HTR2A) and tryptophan hydroxylase (TPH) genes for association with suicidal behavior in depressive patients....
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