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Article

Suicide attempt, clinical correlates, and BDNF Val66Met polymorphism in chronic patients with schizophrenia.

Neuropsychology - 1 Feb 2018

Xia Haisen, Zhang Guangya, Du Xiangdong, Zhang Yingyang, Yin Guangzhong, Dai Jing, He Man-Xi, Soares Jair C, Li Xiaosi, Zhang Xiang Yang

Abstract excerpt

OBJECTIVE: Recent evidence suggests the role of brain-derived neurotrophic factor (BDNF) in the pathophysiology of suicidal behavior. Because schizophrenia patients usually have high suicide rates and numerous studies have suggested that BDNF may contribute to the psychopathology of schizophrenia, we hypothesized that the functional polymorphism of BDNF (Val66Met) was associated with suicide attempts in patients...

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Identifiers

PMID: 28857598
DOI: 10.1037/neu0000383

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BDNF

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