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Article

Chemokine ligand 2 genetic variants, serum monocyte chemoattractant protein-1 levels, and the risk of coronary artery disease.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2010

van Wijk Diederik F, van Leuven Sander I, Sandhu Manjinder S, Tanck Michael W, Hutten Barbara A, Wareham Nicholas J, Kastelein John J P, Stroes Erik S G, Khaw Kay-Tee, Boekholdt S Matthijs

Abstract excerpt

OBJECTIVE: In humans, evidence about the association between levels of monocyte chemoattractant protein-1 (MCP-1), its coding gene chemokine (C-C motif) ligand 2 (CCL2), and risk of coronary artery disease (CAD) is contradictory. METHODS AND RESULTS: We performed a nested case-control study in the prospective EPIC-Norfolk cohort investigating the relationship between CCL2 single-nucleotide polymorphisms (SNPs),...

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Identifiers

PMID: 20431065
DOI: 10.1161/ATVBAHA.110.205526
PMCID: PMC4210837

Genes

CAD
CCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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