Article
Association of CCR2 polymorphisms with the number of closed coronary artery vessels in coronary artery disease.
Clinica chimica acta; international journal of clinical chemistry - 1 Jul 2007
Cha Seung-Hun, Lee Jong-Keuk, Lee Jong-Young, Kim Hung Tae, Ryu Ha-Jung, Han Bok Ghee, Kim Jun Woo, Oh Bermseok, Kimm Kuchan, Shin Hyung-Doo, Park Byung Lae, Park Sungha, Park Hyun-Young, Jang Yangsoo
Abstract excerpt
Coronary artery disease (CAD) is one of the most common forms of heart disease. It has been demonstrated that chemokine-mediated inflammation is associated with the development of CAD. In this study, in order to determine the role of CCR2, a receptor for MCP-1, in the development of CAD, we initially sequenced and identified the genetic variants of CCR2 using 24 unrelated Korean individuals' DNA samples. A total...
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