Article
Examination of genetic effects of polymorphisms in the MCP-1 and CCR2 genes on MI in the Icelandic population.
Atherosclerosis - 1 Oct 2006
Bjarnadottir Kristjana, Eiriksdottir Gudny, Aspelund Thor, Gudnason Vilmundur
Abstract excerpt
Monocyte chemotactic protein-1 (MCP-1) and its receptor CCR2 may play a role in mediating atherosclerosis. The polymorphisms MCP-1 -2518A>G and CCR2 190G>A have been reported to be associated with increased risk for developing atherosclerosis. The aim of this study was to investigate the effect of these polymorphisms and the MCP-1 -2076A>T polymorphism on the development of myocardial infarction (MI) in an...
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