Article
Understanding the role of circulating chemokine (C-C motif) ligand 2 in patients with chronic ischemia threatening the lower extremities.
Vascular medicine (London, England) - 1 Dec 2014
Rull Anna, Hernandez-Aguilera Anna, Fibla Montserrat, Sepulveda Julio, Rodríguez-Gallego Esther, Riera-Borrull Marta, Sirvent Juan J, Martín-Paredero Vicente, Menendez Javier A, Camps Jordi, Joven Jorge
Abstract excerpt
The role of chemokine (C-C motif) ligand 2 (CCL2) in peripheral artery disease is unclear. We measured the difference between serum and plasma levels of CCL2 in patients with chronic ischemia threatening the lower extremities following the observation that atypical chemokine receptors in blood and tissue cells may prevent CCL2 from entering the circulation and consequently modulate its function of attracting...
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