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Article

Assessment of genetic effects of polymorphisms in the MCP-1 gene on serum MCP-1 levels and myocardial infarction in Japanese.

Circulation journal : official journal of the Japanese Circulation Society - 1 Jul 2006

Iwai Naoharu, Kajimoto Kazuaki, Kokubo Yoshihiro, Okayama Akira, Miyazaki Shunichi, Nonogi Hiroshi, Goto Yoichi, Tomoike Hitonobu

Abstract excerpt

BACKGROUND: Recently, the Framingham Heart Study reported that genetic variations in CCL2 influence serum levels of monocyte chemoattractant protein-1 (MCP-1) and the incidence of myocardial infarction (MI). The purpose of the present study was to investigate the possible involvement of CCL2 in the pathogenesis of atherosclerosis and MI in Japanese. METHODS AND RESULTS: Multiple regression analysis indicated that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16799229
DOI: 10.1253/circj.70.805

Genes

CCL2

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