Article
Macrophage migration inhibitory factor (MIF) and risk for coronary heart disease: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002.
Atherosclerosis - 1 Oct 2008
Herder Christian, Illig Thomas, Baumert Jens, Müller Martina, Klopp Norman, Khuseyinova Natalie, Meisinger Christa, Martin Stephan, Thorand Barbara, Koenig Wolfgang
Abstract excerpt
OBJECTIVE: Macrophage migration inhibitory factor (MIF), a central cytokine of the innate immunity, has been reported to contribute to the development of cardiovascular disease. MIF is expressed in atherosclerotic lesions in humans, and gene deletion and antibody inhibition studies in animal models indicated that MIF may be cause rather than consequence of atherosclerosis. We sought to assess the triangular...
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