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Article

Polymorphisms in the CC-chemokine receptor-2 (CCR2) and -5 (CCR5) genes and risk of coronary heart disease among US women.

Atherosclerosis - 1 May 2006

Pai Jennifer K, Kraft Peter, Cannuscio Carolyn C, Manson JoAnn E, Rexrode Kathryn M, Albert Christine M, Hunter David, Rimm Eric B

Abstract excerpt

OBJECTIVE: Genetic variation in CC-chemokine receptor-2 (CCR2) and -5 (CCR5), and their common haplotypes, acting through inflammatory responses, may affect atherosclerosis and risk of coronary heart disease (CHD). METHOD AND RESULTS: We examined seven common variants in the CCR2 and CCR5 loci and risk of CHD among women in the Nurses' Health Study. During 8 years of follow-up, we documented 248 incident cases of...

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Source

Identifiers

PMID: 16055130
DOI: 10.1016/j.atherosclerosis.2005.06.041

Genes

CCR5
CCR2

Variants

rs2856758

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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