Article
Reporter alleles that inform on differences in Cre recombinase expression.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 2010
Klinger Mark, Chmura Stephen A, Killeen Nigel
Abstract excerpt
Alleles that express reporters after Cre recombination allow for fate-mapping studies when used in combination with appropriate cre alleles. In this study, we describe two fluorescent reporter alleles that differentially mark populations of cells as a function of their level of expression of Cre recombinase. Mice carrying these alleles were generated and used to demonstrate the usefulness of the reporter alleles...
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