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Article

Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice.

Disease models & mechanisms - 1 Nov 2012

Serup Palle, Gustavsen Carsten, Klein Tino, Potter Leah A, Lin Robert, Mullapudi Nandita, Wandzioch Ewa, Hines Angela, Davis Ashley, Bruun Christine, Engberg Nina, Petersen Dorthe R, Peterslund Janny M L, Macdonald Raymond J, Grapin-Botton Anne, Magnuson Mark A, Zaret Kenneth S

Abstract excerpt

Extracellular signals in development, physiology, homeostasis and disease often act by regulating transcription. Herein we describe a general method and specific resources for determining where and when such signaling occurs in live animals and for systematically comparing the timing and extent o...

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Identifiers

PMID: 22888097
DOI: 10.1242/dmm.009696
PMCID: PMC3484877

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22888097-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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