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Article

embCAB sequence variation among ethambutol-resistant Mycobacterium tuberculosis isolates without embB306 mutation.

The Journal of antimicrobial chemotherapy - 1 Jul 2010

Plinke Claudia, Cox Helen S, Zarkua Nana, Karimovich Hamraev A, Braker Kai, Diel Roland, Rüsch-Gerdes Sabine, Feuerriegel Silke, Niemann Stefan

Abstract excerpt

OBJECTIVES: Mechanisms of resistance to ethambutol in Mycobacterium tuberculosis remain inadequately described. Although there is mounting evidence that mutations of codon 306 in embB play a key role, a significant number of phenotypically ethambutol-resistant strains do not carry mutations in this codon. Here, other mutations in the embCAB operon are suggested to be involved in resistance development. METHODS:...

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Identifiers

PMID: 20427375
DOI: 10.1093/jac/dkq120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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