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Article

Association between embB codon 306 mutations and drug resistance in Mycobacterium tuberculosis.

Antimicrobial agents and chemotherapy - 1 Jul 2007

Shen Xin, Shen Guo-miao, Wu Jie, Gui Xiao-hong, Li Xia, Mei Jian, DeRiemer Kathryn, Gao Qian

Abstract excerpt

embB306 mutants were detected in both ethambutol (EMB)-resistant and EMB-susceptible strains of Mycobacterium tuberculosis. Multidrug-resistant (MDR) strains had a higher proportion of embB306 mutants than non-MDR strains (odds ratio, 6.78; P < 0.001). The embB306 locus is a candidate marker for rapid detection of MDR and extremely drug resistant tuberculosis.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17438044
DOI: 10.1128/AAC.01516-06
PMCID: PMC1913254

Genes

EMB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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