Article
Characteristics of embB mutations in multidrug-resistant Mycobacterium tuberculosis isolates in Henan, China.
The Journal of antimicrobial chemotherapy - 1 Oct 2011
Shi Dawei, Li Liang, Zhao Yuling, Jia Qiong, Li Hui, Coulter Christopher, Jin Qi, Zhu Guofeng
Abstract excerpt
OBJECTIVES: To determine the association between embB mutations and drug resistance, and to further investigate the mechanism of embB mutations involved in the development of ethambutol and multidrug resistance in Mycobacterium tuberculosis. METHODS: One hundred and thirty-eight multidrug-resistant clinical M. tuberculosis isolates, including 86 ethambutol-resistant and 52 ethambutol-susceptible strains, were...
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