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Article

Significance of mutations in embB codon 306 for prediction of ethambutol resistance in clinical Mycobacterium tuberculosis isolates.

Antimicrobial agents and chemotherapy - 1 May 2006

Plinke Claudia, Rüsch-Gerdes Sabine, Niemann Stefan

Abstract excerpt

We analyzed 159 Mycobacterium tuberculosis isolates (101 ethambutol [EMB]-resistant strains, 33 multidrug-resistant but not EMB-resistant strains, and 25 fully susceptible strains) for the presence of mutations in embB codon 306 (embB306). Mutations were detected only in EMB-resistant strains (n = 69; 68%), thus confirming the significance of embB306 mutations for the prediction of resistance to EMB.

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Source

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Identifiers

PMID: 16641474
DOI: 10.1128/AAC.50.5.1900-1902.2006
PMCID: PMC1472212

Genes

EMB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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