Article
MicroRNA expression in acute myeloid leukemia.
Current hematologic malignancy reports - 1 Apr 2009
Marcucci Guido, Radmacher Michael D, Mrózek Krzysztof, Bloomfield Clara D
Abstract excerpt
Acute myeloid leukemia (AML) is a group of diseases that are very heterogeneous with regard to cytogenetic aberrations, gene mutations, and changes in expression of numerous genes. A new class of genes known as microRNAs recently was found to be involved in myeloid leukemogenesis. These genes are transcribed into regulatory, noncoding RNAs that control mRNA and protein expression of target genes. Genome-wide...
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