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Article

Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs.

Diabetologia - 1 Feb 2012

Gupta V, Vinay D G, Rafiq S, Kranthikumar M V, Janipalli C S, Giambartolomei C, Evans D M, Mani K R, Sandeep M N, Taylor A E, Kinra S, Sullivan R M, Bowen L, Timpson N J, Smith G D, Dudbridge F, Prabhakaran D, Ben-Shlomo Y, Reddy K S, Ebrahim S, Chandak G R

Abstract excerpt

AIMS/HYPOTHESIS: Evaluation of the association of 31 common single nucleotide polymorphisms (SNPs) with fasting glucose, fasting insulin, HOMA-beta cell function (HOMA-β), HOMA-insulin resistance (HOMA-IR) and type 2 diabetes in the Indian population. METHODS: We genotyped 3,089 sib pairs recruited in the Indian Migration Study from four cities in India (Lucknow, Nagpur, Hyderabad and Bangalore) for 31 SNPs in 24...

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Identifiers

PMID: 22052079
DOI: 10.1007/s00125-011-2355-6
PMCID: PMC3245821

Genes

ADAM30
CDKAL1
CXCR4
NOTCH2

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