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Article

Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort.

PloS one - 10 Feb 2010

Wen Jie, Rönn Tina, Olsson Anders, Yang Zhen, Lu Bin, Du Yieping, Groop Leif, Ling Charlotte, Hu Renming

Abstract excerpt

BACKGROUND: Recent genome-wide association studies (GWASs) have reported several genetic variants to be reproducibly associated with type 2 diabetes. Additional variants have also been detected from a metaanalysis of three GWASs, performed in populations of European ancestry. In the present study, we evaluated the influence of 17 genetic variants from 15 candidate loci, identified in type 2 diabetes GWASs and the...

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Blood Glucose
Cyclin-Dependent Kinase 5
Cyclin-Dependent Kinase Inhibitor p15
Cyclin-Dependent Kinase Inhibitor p16
Logistic Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

TCF Transcription Factors

Transcription Factor 7-Like 2 Protein

tRNA Methyltransferases

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Open in PubMed Open full text

Identifiers

PMID: 20161779
DOI: 10.1371/journal.pone.0009153
PMCID: PMC2818850

Genes

CDKAL1
FTO
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort.PMID 20161779Read ↗

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Validation of type 2 diabetes risk variants identified by genome-wide association studies in Han Chinese population: a replication study and meta-analysis.Semantic proximity Read ↗

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