Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular oncology focus - is carcinogenesis a 'mitochondriopathy'?

Journal of biomedical science - 25 Apr 2010

Czarnecka Anna M, Czarnecki Jerzy S, Kukwa Wojciech, Cappello Francesco, Scińska Anna, Kukwa Andrzej

Abstract excerpt

Mitochondria are sub-cellular organelles that produce adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS). As suggested over 70 years ago by Otto Warburg and recently confirmed with molecular techniques, alterations in respiratory activity and in mitochondrial DNA (mtDNA) appear to be common features of malignant cells. Somatic mtDNA mutations have been reported in many types of cancer cells,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to DNA, Mitochondrial
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitochondria

Share to Mitochondrial Diseases

Share to Mutation

Share to Neoplasms

Share to Oxidative Phosphorylation

Source

Open in PubMed Open full text

Identifiers

PMID: 20416110
DOI: 10.1186/1423-0127-17-31
PMCID: PMC2876137

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular oncology focus - is carcinogenesis a 'mitochondriopathy'?PMID 20416110Read ↗

Mitochondrial DNA mutations in cancer--from bench to bedside.Semantic proximity Read ↗

Mitochondrial DNA mutations in cancer: a review.Semantic proximity Read ↗

Spotlight on the relevance of mtDNA in cancer.Semantic proximity Read ↗

Mitochondrial DNA alterations in precision oncology: Emerging roles in diagnostics and therapeutics.Semantic proximity Read ↗

Generation, function, and prognostic utility of somatic mitochondrial DNA mutations in cancer.Semantic proximity Read ↗

A critical reassessment of the role of mitochondria in tumorigenesis.Semantic proximity Read ↗

Mitochondrial defects in cancer.Semantic proximity Read ↗

Mitochondria act as a key regulatory factor in cancer progression: Current concepts on mutations, mitochondrial dynamics, and therapeutic approach.Semantic proximity Read ↗

Mitochondrial genome instability in cancer.Semantic proximity Read ↗

Functional Role of Mitochondrial DNA in Cancer Progression.Semantic proximity Read ↗

Mitochondrial genome alterations in cancer: From mutations and epigenetics to targeted therapiesack.Semantic proximity Read ↗

Somatic mitochondrial DNA mutations in human cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.