Article
Cannabinoid type-1 receptor gene polymorphisms are associated with central obesity in a Southern Brazilian population.
Disease markers - 1 Jan 2008
Jaeger Janaína P, Mattevi Vanessa S, Callegari-Jacques Sidia M, Hutz Mara H
Abstract excerpt
The CB1 cannabinoid receptor and its endogenous ligands, the endocannabinoids, are involved in energy balance control, stimulating appetite and increasing body weight in wasting syndromes. Different studies have investigated the relationship between polymorphisms of the cannabinoid receptor 1 (CNR1) gene and obesity with conflicting results. In the present study, we investigated the 1359G/A (rs1049353), 3813A/G...
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