Article
The G1422A variant of the cannabinoid receptor gene (CNR1) is associated with abdominal adiposity in obese men.
Endocrine - 1 Apr 2007
Peeters Armand, Beckers Sigri, Mertens Ilse, Van Hul Wim, Van Gaal Luc
Abstract excerpt
Since recent data suggest that the endocannabinoid system controls food intake through central, and lipogenesis via peripheral CB1 receptors, we hypothesized that genetic variation at the cannabinoid receptor-1 (CNR1) locus could have an effect on adiposity. We investigated, whether a specific CNR1 G1422A genotype is associated with anthropometric markers of obesity and fat distribution in adult obese...
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