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Article

Apolipoprotein e3 as a risk factor for Alzheimer's disease under conditions of nutritional imbalance.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Chan Amy, Shea Thomas B

Abstract excerpt

The presence of one or more copies of the E4 allele of apolipoprotein E (ApoE) is strongly associated with of Alzheimer's disease (AD). The impact of E4 on neurodegeneration is potentiated by dietary oxidative challenge. Our prior studies in transgenic mice demonstrate that, in the face of dietary oxidative challenge, E3 does not provide any further protection than E4 or lack of murine ApoE for aggression,...

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Identifiers

PMID: 20413864
DOI: 10.3233/JAD-2010-100060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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