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Obesity Accelerates Alzheimer-Related Pathology inAPOE4but notAPOE3Mice

1 May 2017

Abstract excerpt

Abstract Alzheimer’s disease (AD) risk is modified by both genetic and environmental risk factors, which are believed to interact to cooperatively modify pathogenesis. Although numerous genetic and environmental risk factors for AD have been identified, relatively little is known about potential gene-environment interactions in regulating disease risk. The strongest genetic risk factor for late-onset AD is the ε4...

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PMID: 28612048
DOI: 10.1523/eneuro.0077-17.2017

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