Article
Advances in the prediction and natural history of type 1 diabetes.
Endocrinology and metabolism clinics of North America - 1 Sept 2010
Bonifacio Ezio, Ziegler Anette G
Abstract excerpt
Type 1 diabetes (T1D) has the hallmark characteristics of autoimmunity superimposed on genetic susceptibility. Both genes (HLA) and immune markers (autoantibodies) have been validated as predictive markers of the subsequent development of the disease in higher-risk relatives and the lower-risk general population. Over the last three decades, using a combination of genes, immune, and metabolic markers, clinicians...
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