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Article

The pathophysiology, presentation and classification of Type 1 diabetes.

Diabetes, obesity & metabolism - 1 Aug 2025

Aamodt Kristie I, Powers Alvin C

Abstract excerpt

Type 1 diabetes is characterised by the autoimmune destruction of pancreatic β-cells, leading to an absolute or near-absolute insulin deficiency. Although traditionally associated with childhood onset, it can manifest at any age, and it is increasingly recognised that there is significant heterogeneity in its clinical presentation. This review examines the intricate interplay between genetic susceptibility,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 40734585
DOI: 10.1111/dom.16628
PMCID: PMC12312824

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