Article
Identification of the Slynar gene (AY070435) and related brain expressed sequences as a candidate gene for susceptibility to affective disorders through allelic and haplotypic association with bipolar disorder on chromosome 12q24.
The American journal of psychiatry - 1 Oct 2006
Kalsi Gursharan, McQuillin Andrew, Degn Birte, Lundorf Mikkel D, Bass Nicholas J, Lawrence Jacob, Choudhury Khalid, Puri Vinay, Nyegaard Mette, Curtis David, Mors Ole, Kruse Torben, Kerwin Simon, Gurling Hugh
Abstract excerpt
OBJECTIVE: Three linkage studies of bipolar disorder have implicated chromosome 12q24.3, with significant lod scores of over 3.00. Several other linkage studies have found lod scores between 2.00 and 3.00. In order to identify which gene on this chromosome is responsible, the authors carried out tests of allelic association with bipolar disorder in order to fine map an affective disorder susceptibility gene....
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