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Article

A genome-wide scan points to a susceptibility locus for bipolar disorder on chromosome 12.

Molecular psychiatry - 1 Jun 2005

Shink E, Morissette J, Sherrington R, Barden N

Abstract excerpt

Our previous results pointed to a putative gene for susceptibility to bipolar affective disorder located on the chromosomal region 12q23-q24 that segregated in the Saguenay-Lac-St-Jean population of Quebec. We report here results from a second genome-wide scan based on the analysis of 380 polymorphic microsatellite markers. For the purpose of this analysis, an additional 18 families were recruited from the...

Topics

Adult
Bipolar Disorder
Chromosomes, Human, Pair 12
Genetic Linkage
Genetic Predisposition to Disease
Genetic Testing
Genome
Humans
Lod Score
Microsatellite Repeats
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Genetic

Pedigree

Polymorphism, Genetic

Quebec

Source

Identifiers

PMID: 15494705
DOI: 10.1038/sj.mp.4001601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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A genome-wide scan points to a susceptibility locus for bipolar disorder on chromosome 12.PMID 15494705Read ↗

Analysis of microsatellite markers and single nucleotide polymorphisms in candidate genes for susceptibility to bipolar affective disorder in the chromosome 12Q24.31 region.Semantic proximity Read ↗

Genome-wide search for linkage of bipolar affective disorders in a very large pedigree derived from a homogeneous population in quebec points to a locus of major effect on chromosome 12q23-q24.Semantic proximity Read ↗

Support for a bipolar affective disorder susceptibility locus on chromosome 12q24.3.Semantic proximity Read ↗

A genome screen of a large bipolar affective disorder pedigree supports evidence for a susceptibility locus on chromosome 13q.Semantic proximity Read ↗

Family-based association study for bipolar affective disorder.Semantic proximity Read ↗

Genome-wide scan for genes involved in bipolar affective disorder in 70 European families ascertained through a bipolar type I early-onset proband: supportive evidence for linkage at 3p14.Semantic proximity Read ↗

A possible susceptibility locus for bipolar affective disorder in chromosomal region 10q25--q26.Semantic proximity Read ↗

A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19.Semantic proximity Read ↗

A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19.Semantic proximity Read ↗

A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q.Semantic proximity Read ↗

A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2.Semantic proximity Read ↗

Scanning the genome with 1772 microsatellite markers in search of a bipolar disorder susceptibility gene.Semantic proximity Read ↗

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