Article
An IFT-A protein is required to delimit functionally distinct zones in mechanosensory cilia.
Current biology : CB - 23 Dec 2008
Lee Eugene, Sivan-Loukianova Elena, Eberl Daniel F, Kernan Maurice J
Abstract excerpt
BACKGROUND: Conserved intraflagellar transport (IFT) particle proteins and IFT-associated motors are needed to assemble most eukaryotic cilia and flagella. Proteins in an IFT-A subcomplex are generally required for dynein-driven retrograde IFT, from the ciliary tip to the base. We describe novel structural and functional roles for IFT-A proteins in chordotonal organs, insect mechanosensory organs with cilia that...
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