Article
A polymorphism in the gene for the atrial natriuretic peptide and diabetic nephropathy. Diabetic Nephropathy Study Group.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jul 1998
Schmidt S, Blüthner M, Giessel R, Strojek K, Bergis K H, Grzeszczak W, Ritz E
Abstract excerpt
BACKGROUND: Atrial natriuretic peptide is involved in blood pressure regulation via its vasodilating and natriuretic actions. Since diabetic nephropathy and hypertension are closely related, ANP is a reasonable candidate gene for diabetic nephropathy (DN). METHODS: We genotyped 410 patients with...
Topics
- Adult
- Alleles
- Atrial Natriuretic Factor
- DNA Primers
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Female
- Gene Frequency
- Genotype
- Humans
