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Article

Association of CYP2C9 polymorphisms with phenytoin toxicity in Indian patients.

Neurology India - 1 Jan 2000

Thakkar Akanksha N, Bendkhale Shital R, Taur Santosh R, Gogtay Nithya J, Thatte Urmila M

Abstract excerpt

BACKGROUND: Genetic polymorphisms of CYP2C9 can lead to wide inter-individual variations in drug metabolism. Decreased metabolism leads to higher plasma levels, causing adverse drug reactions (ADRs). Polymorphic alleles CYP2C9 FNx01 2 and CYP2C9 FNx01 3 occur in the Indian population and this may serve as the basis for using genotyping as a tool to predict phenytoin toxicity. AIMS: To evaluate the association...

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Source

Identifiers

PMID: 23287317
DOI: 10.4103/0028-3886.105189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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