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Article

The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.

PloS one - 13 Apr 2010

Handel Adam E, Handunnetthi Lahiru, Berlanga Antonio J, Watson Corey T, Morahan Julia M, Ramagopalan Sreeram V

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is a complex neurological disorder. Its aetiology involves both environmental and genetic factors. Recent genome-wide association studies have identified a number of single nucleotide polymorphisms (SNPs) associated with susceptibility to (MS). We investigated whether these genetic variations were associated with alteration in gene expression. METHODS/PRINCIPAL FINDINGS: We...

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Identifiers

PMID: 20405052
DOI: 10.1371/journal.pone.0010142
PMCID: PMC2854120

Genes

TSFM
ZFP57

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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